Electrochemical paper-based antigen sensing platform using plant-derived monoclonal antibody for detecting SARS-CoV-2Article Published on 2023-01-012022-11-15 Journal: Talanta [Category] SARS, 진단, 치료기술, 치료제, [키워드] anti-SARS-CoV-2 antibody Antigen applicability applied approach Cellulose Concentration COVID-19 diagnosis CR3022 detect diagnostic Differential pulse voltammetry expressed functional group limit of detection linear relationship monoclonal antibody nasopharyngeal swab sample Nicotiana benthamiana Paper-based electrochemical immunosensor Plant-based antibody platform point-of-care pulse quantification RBD Receptor binding domain Saliva SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2. Spike protein the RBD this system was performed [DOI] 10.1016/j.talanta.2022.123783 PMC 바로가기
The efficacy and effectiveness of the COVID-19 vaccines in reducing infection, severity, hospitalization, and mortality: a systematic review감염, 중증도, 입원 및 사망률 감소에 대한 COVID-19 백신의 효능 및 효과: 체계적인 검토Article Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 변종, [키워드] accelerated approved B.1.1.7 B.1.351 B.1.351 variants COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines database disease transmission effective Effectiveness Efficacy effort growth Hospitalization identify inclusion criteria Infection infections Mortality Pfizer Pfizer/BioNTech populations reduced reducing regimen required Seven severity systematic literature search systematic review Vaccine Vaccine development vaccine. Vaccines variants was performed [DOI] 10.1080/21645515.2022.2027160 PMC 바로가기 [Article Type] Article
Sudden unexpected death in a 17-year-old boy due to unacknowledged adamantinoma-like Ewing sarcomaArticle Published on 2022-12-012022-11-15 Journal: Forensic Science, Medicine, and Pathology [Category] COVID19(2023년), SARS, 바이오마커, 진단, 치료기술, [키워드] Abnormalities Adamantinoma-like Ewing sarcoma addition airway Airway occlusion Analysis analysis anatomical Autopsy Blood Brain break cardiac cause CD99 Cell characterized Chest radiography Complete death diagnosed diagnostic diagnostics died discharged disease Dyspnea EWSR1 excluded expression Forensic Forensic autopsy forensic pathology Germany histopathological hospital immunohistochemistry Invasion Leica Local lung macroscopic male mechanism Microscopy Mild molecular Nasopharyngeal swab neoplasm nucleoli organ oxygen saturation pathology probe SARS-CoV-2 Soft tissue subject sudden Sudden unexpected death. tested Thyroid was performed [DOI] 10.1007/s12024-022-00525-x PMC 바로가기
Identification of the Hub Genes and the Signaling Pathways in Human iPSC-Cardiomyocytes Infected by SARS-CoV-2Article Published on 2022-12-012022-11-16 Journal: Biochemical Genetics [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Analysis applied Bioinformatics analysis biological process Biomarker Brain caused component Cytoscape software database dataset DEGs differentially expressed gene direct infection down-regulated gene enrichment analysis function Gene Expression Omnibus gene expression profile Gene ontology Genes GEO GraphPad Prism software High-throughput sequencing hub genes Human Human iPSC-cardiomyocytes identification infected with SARS-CoV-2 intestine KEGG kidney Kyoto Ligand liver Lung injury mechanisms myocardial injury organ pathway Pathways PPI PPI network protein-protein interaction R software receptor Research respiratory respiratory symptom SARS-CoV-2 SARS-CoV-2. screened sequencing data signaling pathway single-stranded RNA virus statistical analysis statistically significant TNF signaling Type type I interferon up-regulated was obtained was performed website [DOI] 10.1007/s10528-022-10206-7 PMC 바로가기
Identification of circulating microRNA profiles associated with pulmonary function and radiologic features in survivors of SARS-CoV-2-induced ARDSSARS-CoV-2에 의해 유발된 ARDS 생존자의 폐 기능 및 방사선학적 특징과 관련된 순환 microRNA 프로파일 식별Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 유전자 메커니즘, 임상, [키워드] acute respiratory distress syndrome Anti-inflammatory ARDS association carbon monoxide cell death Chest computed tomography circulating Coagulation Complete composed Computed tomography conducted correlated COVID-19 develop diffusing diffusing capacity distress enrichment analyses enrichment analysis evaluated Evidence evidence of feature Features Follow-up Gene ontology genomes hospital discharge hypoxia identification immune response infected patient infected patients KEGG KEGG pathway Kyoto lung Lung function median microRNA miR-126 miR-146 miR-146a-5p miR-21 miR-9 miRNA miRNA profiles miRNA profiling miRNA signature molecular molecular mechanism molecular mechanisms Pathogenesis pathophysiology pathway Patient patients predicted profile provided Pulmonary function radiologic radiological feature radiological features Random forest respiratory distress Respiratory distress syndrome RT-qPCR SARS-COV-2 infection secondary to sequelae severe COVID-19 severity survivor to define total severity score. Trial registration TSS vascularization viral infection was performed was used [DOI] 10.1080/22221751.2022.2081615 PMC 바로가기 [Article Type] Article
Statistical analysis supports UTR (untranslated region) deletion theory in SARS-CoV-2Article Published on 2022-12-012022-11-16 Journal: Virulence [Category] COVID19(2023년), SARS, 변종, [키워드] affected Analysis ancestor Asymptomatic asymptomatic patients clinical outcomes correlation Degradation deletion of the untranslated region demonstrated Deterioration driving early stage evaluate Evolution explain genetic influence Genome hospitalized patient indicated mathematical Mortality mortality rate Mutation nucleic acid nucleic acid degradation system Patient SARS-CoV-2 SARS-COV-2 infection significantly significantly more similarity strain Support Symptoms the epidemic Toxicity UTR viral genome viral toxicity viral toxicity. virulence virus virus genome was performed [DOI] 10.1080/21505594.2022.2132059 PMC 바로가기
Low BALF CD4 T cells count is associated with extubation failure and mortality in critically ill covid-19 pneumonia낮은 BALF CD4 T 세포 수는 중환자의 covid-19 폐렴에서 발관 실패 및 사망률과 관련이 있습니다Article Published on 2022-12-012022-09-11 Journal: Annals of Medicine [Category] 바이오마커, 진단, [키워드] affected alveolar alveolar macrophage analysed average BALF BALF CD4 T-cells count baseline Biomarker bivariate analysis Bronchoalveolar lavage fluid caspase caspase-3 cause CD4 CD4 T cell CD4 T-cell Characteristics clinical Clinical characteristics conducted COVID-19 COVID-19 patients COVID-19 pneumonia COVID-19 pneumonia patient COVID-19 pneumonia patients Critically ill critically ill COVID-19 patients Critically ill COVID-19 pneumonia D-dimer D-dimer level eight enrolled extubation failure. groups help IL-17 IL-6 immunopathology IMPROVE Indonesia intubation Invasive mechanical ventilation Laboratory lung Macrophage material Mortality no significant difference no significant differences outcome Patient performed Pneumonia profile Referral reported right lung severe pneumonia severity significant differences significantly survived T-cells Tertiary Tregs understanding was performed were measured [DOI] 10.1080/07853890.2022.2095012 PMC 바로가기 [Article Type] Article
Reliable estimation of SARS-CoV-2 anti-spike protein IgG titers from single dilution optical density values in serologic surveysArticle Published on 2022-12-012022-11-15 Journal: Diagnostic microbiology and infectious disease [Category] COVID19(2023년), SARS, 진단, [키워드] anti-spike protein IgG antibody approach Brazil change changes in Community-based cohort conducted decrease Dilution dilutions ELISA evaluate fitting IgG ELISA Immunity incidence increase interpolated MONITOR normalized optical optical density pandemic Participants predicted reduce reliability resource SARS-CoV-2 sera serial dilutions serology Serosurvey significantly titers Titers. was performed [DOI] 10.1016/j.diagmicrobio.2022.115807 PMC 바로가기
Influenza and other respiratory viruses in children: prevalence and clinical featuresArticle Published on 2022-12-012022-11-15 Journal: European Journal of Clinical Microbiology & Infect [Category] 신종인플루엔자, 진단, 치료기술, [키워드] age ARI Asthma clinical feature clinical manifestation collected cough COVID-19 pandemic Epidemic Epidemics Epidemiology female H1N1 ICU Infection Influenza influenza A influenza B other respiratory virus Patient positive Prevalence prevalent real-time RT-PCR respiratory respiratory infection respiratory virus respiratory virus respiratory viruses rhinoviruses RNA extraction specimens study period surveillance. tested virus was performed [DOI] 10.1007/s10096-022-04515-3 PMC 바로가기
SARS-CoV-2 reinfection and COVID-19 severitySARS-CoV-2 재감염 및 COVID-19 심각성Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] antibodies antibody clinical recovery clinical symptom Clinical symptoms coronavirus COVID-19 COVID-19 severity diagnosed early stage episode of Frequency Hospitalization ICU Infection infections negative RT-PCR no difference no differences Patient patients patients with SARS-CoV-2 performed positive positive RT-PCR Reinfection RT-PCR SARS-CoV-2 SARS-CoV-2 positive RT-PCR serology Seven severity Severity of infection Severity. transfer variant was performed were infected Whole genome sequencing [DOI] 10.1080/22221751.2022.2052358 PMC 바로가기 [Article Type] Article